IgM is the colossus of immunoglobulins, making up approximately 13 to 15% of serum antibodies. Importantly, it is also the first line of defense among the immunoglobulin family, being the first immunoglobulin made during a typical immunological response. In the COVID-19 outbreak, IgM/IgG detection has provided a quick, simple, and accurate detection method for suspected COVID-19 cases.
IgM antibodies show great potential in disease therapy development, vaccine development, and clinical diagnosis as they function to agglutinate invading material, compel individual pieces to stick together for easier clearing from the body, as well as promote lysis and phagocytosis of micro-organisms. To help unleash the full potential of IgM, Creative Biolabs strives to offer efficient, cost-effective solutions on IgM-related programs with a portfolio of services and products.
The one-stop IgM-related service covers the whole pipeline of therapeutic antibody development from antibody discovery, engineering, production, purification, characterization to PK/PD evaluation. The scientist team at Creative Biolabs will offer a fully customizable experimental design to expand beyond standard procedure for programs of worldwide researchers.
Creative Biolabs is also dedicated to offering a wide spectrum of in vitro diagnostic (IVD) antibody products to illustrate antibody bioactivity and mechanism of action, and has been focusing on designing and manufacturing high-quality recombinant IgM antibodies with different formats to satisfy the specific requirements.
Featured products include:
Mouse Anti-TERT Monoclonal Antibody (2C4)
*It is an unconjugated anti-TERT Monoclonal antibody generated from the Mouse. This antibody can be used for WB, FC, IF, IHC, IP, ChIP.
Rat Anti-Mouse CD45 Monoclonal Antibody (GL24)
*It is an unconjugated anti-Mouse CD45 Monoclonal antibody generated from the Rat. This antibody can be used for FC, IP.
Rat Anti-Human SSEA-3 Monoclonal Antibody (MC-631)
*It is an unconjugated anti-Human SSEA-3 Monoclonal antibody generated from the Rat. This antibody can be used for WB, FC, IF, IHC, IP.
In addition to IgM antibody products, other non-IgG products covering IgA and IgE antibodies can be found at Creative Biolabs as well.
The right partner can help researchers win the race to reach patients first, and Creative Biolabs strives to be the premier partner on IgM-related programs. Learn more from the official website: https://non-igg-ab.creative-biolabs.com/.
About Creative Biolabs
Empowered by leading technology and years of experience in biomedical science, Creative Biolabs is skilled at providing non-IgG therapeutic antibody development services with the support of the cutting-edge Antibody GlycoOpitimize Platform and Expression System Platform. High-quality off-the-shelf non-IgG products (mainly IgA, IgM, and IgE monoclonal/polyclonal antibodies) and non-IgG antibody ELISA kits are also available for both academic and commercial usage.
Disclaimer: The views, suggestions, and opinions expressed here are the sole responsibility of the experts. No Weekly Optimist journalist was involved in the writing and production of this article.